News on Wellness

Gene Called KL-VS Make Us Smarter And More Intelligent: Study


A recent research done by a team of San Francisco researchers state that people who have KLOTHO gene variant, an enzyme that in humans is encoded by the KL gene, called KL-VS, are smarter, more intelligent and more superior than their friends, relatives and peers.


According to the findigs published in the journal Cell Report scientists believe that this gene which could possibly be the cognitive enhancer be used to boost intelligence in people who have undergone cognitive decline due to diseases or due to ageing. Researchers states that this variant of Klotho gene, can be found in one in five people.

A study conducted on of more than 700 people ages 52 to 85, revealed that those with the gene variant performed better on a variety of cognitive tests than those without it.

“These surprising results pave a promising new avenue of research,” said Roderick Corriveau, PhD, program director at NIH’s National Institute of Neurological Disorders and Stroke (NINDS). “Although preliminary, they suggest klotho could be used to bump up cognition for people suffering from dementia.”

Senior author Lennart Mucke, MD, who directs neurological research at the Gladstone Institutes and a professor of neurology and the Joseph B. Martin Distinguished Professor of Neuroscience at UCSF, stated that Klotho had the capacity to increase cognition, but it does not provide a solution to decline that is related to ageing. Precisely, it means that people with this gene variant have high level of intelligence and cognitive reserve and hence the decline is from higher ground making it look less pronounced.

“Based on what was known about klotho, we expected it to affect the brain by changing the aging process,” Dr. Lennart Mucke said. “But this is not what we found, which suggested to us that we were on to something new and different.”

The study was funded by the Coulter-Weeks Foundation, the SD Bechtel, Jr., Foundation, the National Institutes of Health, the MetLife Foundation, the American Federation for Aging Research and the Hillblom Aging Network.

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