News on Wellness

Merck Has Come Up With New Formula To Treat Hepatitis C!


The US drugmaker, Merck and Co has come up with new formulation of two drugs to treat Hepatitis C better.  Results of the study claim to have cured 98% of patients in the midstage clinical trial, whose who had no history of cirrhosis.  The company has presented the results at the European Association for the Study of the Liver (EASL) in London recently.


Phase 2 study was conducted on a group of 43-44 patients. They were given a combination of two molecules, MK-5172 and MK-8742, of 100 and 50 milligrams each for twelve days. There were no detectable levels of Hepatitis C after completion of 12 weeks. The Sustained Virological responses (SVR) were also controlled. Merck pills have been able to treat difficult patients except one who had relapsed later.

Moreover the current standard treatment takes around 24 to 48 weeks to cure and statistics say could only treat 75% of the patients. As a response to the horrible side effects, most people stop pursuing the medications. Symptoms of flu, influenza like side effects and anemia are the complaints that patients face with the available medications. Pharmaceutical companies are trying to make ribavirin and interferon free drugs, in oral modes of treatment, to combat harmful effects.

The other competitors in the global market are AbbVie, Bristol-Myers Squibb Co and Gilead Sciences Inc who are also developing new generation of all-oral hepatitis C treatments. There is a competition to show up to 90% effects in patients within the 12 week period of oral administration. Analysts have forecasted the sales of Gilead to go up as high as 9 billion dollars this year after it has claimed to release one pill once a day for Hepatitis C.

Patients have also waited for better and effective drugs and line of treatment will now have a new hope once this drug is released. Merck has received impressive results in clinical trials so far. Around 170 million people suffer from Hepatitis C worldwide. With new anti viral further spread is hoped to be checked.


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