News on Wellness

Potential Key for Solving Recurrent Urinary Tract Infections

Potential Key for Solving Recurrent Urinary Tract Infections

In a recent study lead and conducted by the University of Utah microbiologists, it was found that they could have a probable solution to end recurrent urinary tract infections [UTIs]. Researcher discovered that when chitosan was combined with antibiotics it showed positive results in eradicating reservoir populations of bacteria in mice.

UTIs are known to affect a person when E. coli bacteria cause your bladder to get infected. This causes you to have this persistent urge to pass urine and also is extremely painful when you do so. Women are at much greater risk for contracting this infection than men. This could be due the shortness in the length of the urethra in women as compared to men.

Potential Key for Solving Recurrent Urinary Tract Infections

Those infected with UTIs often turn to antibiotics to relieve themselves of the pain. But this might not always be effective to the fullest degree. IT may not work to eradicate the bacteria nesting deep inside the bladder’s cell layers. The lead author of the study Matthew Blango, a University of Utah postdoctoral fellow, told, “We do know that 25 percent [of UTI sufferers] will have a recurrent infection within six months, which tells us the antibiotics aren’t completely clearing the infection.”

In a search to find a solution to this problem, researchers went on to evauate the results of the effects of various antibiotics when combined with chitosan. This is derived from shellfish that has been known to be used as a drug carrier. What they found was that prescribed drugs like sparfloxacin and ciprofloxacin produced the most effective results to eliminate the bacteria in the bladder.

What the chitosan essentially does is exfoliates the protective epithelial cells in the bladder and this gives way to the antibiotics to g deeper and eliminate the bacteria. “What we’re doing is a little different than you might expect,” Blango said. “Usually you don’t try to destroy a layer of cells to treat infection, but in this case, at least in mice, it seems to help the issue.”

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